Across TCGA pan-cancer cohorts, LINC01291 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC01291’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01291 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01291 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, READ, and ESCA are the cancer types where LINC01291 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01291 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.497	.016	3	view →
READ	All	III,IV	+0.960	.011	2	view →
ESCA	Female	All	+1.696	.001	1	view →
KICH	All	All	−0.601	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: LINC01291 RNA expression & survival · all LINC01291 data types