LINC01289

Across TCGA pan-cancer cohorts, LINC01289 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC01289’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC01289 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01289 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

LUSC, COAD, and READ are the cancer types where LINC01289 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01289 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.027	<.001	6	view →
COAD	All	All	−0.122	<.001	5	view →
READ	All	III,IV	−0.169	.003	4	view →
HNSC	All	IV	+0.009	.024	3	view →
LUAD	All	All	+0.006	.026	2	view →
THCA	All	All	−0.009	.047	1	view →
BRCA	Female	All	−0.006	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LINC01289–LUSC

Open the LUSC breakdown →