LINC01281

Across TCGA pan-cancer cohorts, LINC01281 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LINC01281’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC01281 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01281 is over-expressed in tumor.

LUAD, KIRC, and HNSC are the cancer types where LINC01281 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01281 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	+0.437	<.001	9	view →
KIRC	All	II,III,IV	+0.185	<.001	9	view →
HNSC	All	II,III,IV	+0.146	<.001	9	view →
BRCA	All	II,III,IV	+0.287	<.001	6	view →
ESCA	All	All	+0.302	.024	5	view →
STAD	Female	All	+0.541	.010	4	view →
LUSC	All	All	+0.172	.009	3	view →
LIHC	All	All	+0.032	.033	3	view →
COAD	All	All	+0.077	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

LINC01281–LUAD

Open the LUAD breakdown →