long intergenic non-protein coding RNA 1280Genealiases: []
Q-omics provides the consensus-scored LINC01280 profile across patient tissues and cancer cell-line models. LINC01280 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, LINC01280 is differentially expressed in 5, with the highest sampling consensus in HNSC. Additionally, LINC01280 RNA expression shows 6,814 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight THCA, HNSC, and STAD as cancer lineages where LINC01280 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01280 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01280 survival associations across molecular data types. LINC01280 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01280 RNA expression–survival associations across cancer types. High LINC01280 expression shows unfavorable associations in THCA, SARC, ACC, KIRC and BLCA, but favorable associations in LUSC. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify THCA as the clearest survival context for LINC01280 RNA expression.
This table summarizes LINC01280 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01280. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01280 shows higher tumor expression in HNSC, KIRC, LUSC, LUAD and COAD. The HNSC box plot shows higher LINC01280 RNA expression in tumor versus normal tissue (log2 FC = +0.069, t-test p = .004).
This table shows molecular features associated with LINC01280 in patient tissues and cancer cell lines. In patient samples, LINC01280 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
