LINC01271

Across TCGA pan-cancer cohorts, LINC01271 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated LINC01271 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LINC01271 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC01271 expression acts as an unfavorable survival marker, although some lineages such as UCS and MESO show a favorable association.

UVM, KIRC, and KIRP are the cancer types where LINC01271 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.395	0.811	<.001	132	view →
KIRC	DFS	Median	All	0.514	0.714	<.001	116	view →
KIRP	OS	Median	All	0.565	0.801	<.001	79	view →
LGG	OS	Median	All	0.721	0.893	<.001	54	view →
CESC	DFS	Tertile	All	0.445	0.708	<.001	38	view →
COAD	OS	Median	All	0.697	0.882	.001	29	view →
GBM	DFS	Quartile	All	0.191	0.341	.004	24	view →
UCS	DFS	Tertile	IV	0.942	0.462	.024	12	view →
LAML	DFS	Quartile	All	0.194	0.455	.003	10	view →
TGCT	DFS	Quartile	All	0.541	0.860	.003	10	view →
LIHC	OS	Quartile	All	0.707	0.870	.006	9	view →
MESO	OS	Median	II,III,IV	0.386	0.211	.014	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

LINC01271–UVM (DFS)

Open the UVM breakdown →