LINC01238

Across TCGA pan-cancer cohorts, LINC01238 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC01238’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01238 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01238 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

KIRC, THCA, and KICH are the cancer types where LINC01238 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01238 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.182	<.001	11	view →
THCA	All	II,III,IV	−0.877	<.001	8	view →
KICH	All	All	−0.332	<.001	7	view →
BRCA	All	II,III,IV	+0.886	<.001	6	view →
BLCA	All	All	−0.412	.005	6	view →
STAD	All	All	+0.193	.016	4	view →
LIHC	Female	II,III,IV	+0.175	.036	3	view →
PRAD	All	All	+0.502	<.001	2	view →
COAD	All	III,IV	−0.487	.032	2	view →
LUAD	All	All	+0.270	.006	2	view →
CHOL	All	All	+0.753	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LINC01238–KIRC

Open the KIRC breakdown →