LINC01222

Across TCGA pan-cancer cohorts, LINC01222 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated LINC01222 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC01222 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01222 expression acts as an unfavorable survival marker, although some lineages such as LUAD and ESCA show a favorable association.

KIRC, LUAD, and UCEC are the cancer types where LINC01222 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.792	0.884	.013	48	view →
LUAD	OS	Tertile	All	0.837	0.657	.003	36	view →
UCEC	OS	Tertile	All	0.262	0.706	<.001	36	view →
BRCA	OS	Tertile	II,III,IV	0.819	0.919	.003	21	view →
COAD	OS	Tertile	III,IV	0.159	0.692	.021	18	view →
SARC	DFS	Tertile	All	0.320	0.611	.008	15	view →
ESCA	DFS	Tertile	II,III,IV	0.528	0.320	.039	12	view →
THYM	OS	Median	All	1.000	0.656	.005	11	view →
DLBC	OS	Median	II,III,IV	1.000	0.542	.025	6	view →
LGG	OS	Tertile	All	0.832	0.903	.034	3	view →
SKCM	DFS	Tertile	II,III,IV	0.114	0.321	.031	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

LINC01222–KIRC (OS)

Open the KIRC breakdown →