LINC01221

Across TCGA patient cohorts, LINC01221 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,852 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC01221-associated GO terms across cancer lineages are Regulation of binding, Regulation of cyclin-dependent protein kinase activity, and Regulation of telomere maintenance in response to DNA damage. Each is linked with LINC01221 in more than 9 cancer types. Because this analysis shows association rather than direction, both LINC01221-to-partner and partner-to-LINC01221 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of binding grouped by LINC01221-low versus LINC01221-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01221→partner) and Y-score (partner→LINC01221) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of binding →	+0.101	+0.122	<.001	<.001	3	10
STAD	Regulation of cyclin-dependent protein kinase activity →	+0.092	+0.120	<.001	<.001	3	9
STAD	Regulation of telomere maintenance in response to DNA damage →	+0.091	+0.124	<.001	<.001	3	9
STAD	Regulation of DNA binding →	+0.093	+0.120	<.001	<.001	3	9
STAD	Regulation of microtubule polymerization →	+0.092	+0.119	<.001	<.001	3	9
STAD	Peptidyl-lysine modification →	+0.099	+0.114	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,852 associations by consensus.

Regulation of binding by LINC01221 expression — STAD

Explore this box plot interactively →