LINC01214

Across TCGA pan-cancer cohorts, LINC01214 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC01214’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01214 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01214 is over-expressed in tumor, although a few such as KIRC and CHOL show the opposite, repressed pattern.

KIRC, LUAD, and BRCA are the cancer types where LINC01214 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01214 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.543	<.001	11	view →
LUAD	All	II,III,IV	+1.052	<.001	7	view →
BRCA	Female	II,III,IV	+0.291	<.001	6	view →
CHOL	All	All	−0.669	<.001	5	view →
LUSC	Male	All	+0.535	<.001	5	view →
HNSC	All	All	−0.748	.016	3	view →
UCEC	All	All	−0.105	.026	2	view →
KICH	All	All	+0.506	.033	1	view →
THCA	All	IV	+0.445	.044	1	view →
KIRP	All	All	−0.326	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC01214–KIRC

Open the KIRC breakdown →