LINC01205

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC01205 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01205-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and ACC1. Each is linked with LINC01205 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01205-to-partner and partner-to-LINC01205 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by LINC01205-low versus LINC01205-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01205→partner) and Y-score (partner→LINC01205) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC14-3-3_beta →-0.123-2.973.011.03531
UCECEGFR_pY1068 →-0.373-3.584.002.00231
UCECACC1 →+0.510+3.013.003.01831
UCECJNK_pT183_Y185 →-0.198-2.446.015.02031
UCECJNK2 →+0.302+3.179.001.01022
UCECNotch1 →+0.224+3.331<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

14-3-3_beta by LINC01205 expression — UCEC

Box plot of 14-3-3_beta in LINC01205-low vs LINC01205-high samples in UCEC.

Explore this box plot interactively →

Exploration