Across TCGA pan-cancer cohorts, LINC01203 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01203’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01203 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01203 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
HNSC, LUSC, and THCA are the cancer types where LINC01203 tumor–normal differential expression is most reproducible.