Across TCGA pan-cancer cohorts, LINC01177 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC01177’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where LINC01177 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01177 is over-expressed in tumor.
UCEC are the cancer types where LINC01177 tumor–normal differential expression is most reproducible.