LINC01166

Across TCGA pan-cancer cohorts, LINC01166 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC01166’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC01166 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01166 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

LUAD, THCA, and LUSC are the cancer types where LINC01166 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01166 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	−0.410	<.001	8	view →
THCA	Male	III,IV	−0.200	<.001	8	view →
LUSC	Male	All	−0.359	<.001	6	view →
KICH	All	III,IV	−0.091	<.001	6	view →
HNSC	All	All	−0.045	.007	5	view →
UCEC	All	All	−0.357	.010	4	view →
CHOL	All	All	+0.157	.040	4	view →
COAD	Male	All	−0.025	.034	4	view →
KIRC	Male	All	−0.060	.001	3	view →
PRAD	All	All	−0.054	.005	2	view →
STAD	Female	All	−0.047	.034	2	view →
ESCA	All	All	−0.084	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LINC01166–LUAD

Open the LUAD breakdown →