Across TCGA pan-cancer cohorts, LINC01153 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01153’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where LINC01153 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01153 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.
THCA and COAD are the cancer types where LINC01153 tumor–normal differential expression is most reproducible.