LINC01149

Across TCGA pan-cancer cohorts, LINC01149 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01149’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC01149 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01149 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

LUSC, HNSC, and THCA are the cancer types where LINC01149 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01149 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	−0.039	.002	5	view →
HNSC	All	II,III,IV	+0.006	.022	5	view →
THCA	Female	All	−0.024	.026	2	view →
KIRC	All	IV	+0.013	.022	2	view →
STAD	All	II,III,IV	+0.037	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC01149–LUSC

Open the LUSC breakdown →