LINC01144

Across TCGA pan-cancer cohorts, LINC01144 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC01144’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC01144 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01144 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and KIRC are the cancer types where LINC01144 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01144 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−1.337	<.001	11	view →
KICH	Male	All	−1.830	<.001	8	view →
KIRC	Male	II,III,IV	−0.778	<.001	7	view →
LIHC	All	All	+0.393	<.001	7	view →
BLCA	All	All	+0.605	.009	6	view →
CHOL	All	All	+0.542	.004	4	view →
BRCA	Female	II,III,IV	−0.247	.010	4	view →
KIRP	All	All	−0.680	<.001	3	view →
LUSC	All	All	+0.419	.001	3	view →
COAD	All	IV	−0.268	.003	3	view →
LUAD	All	II,III,IV	−0.296	.009	2	view →
PRAD	All	All	+0.221	.040	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC01144–THCA

Open the THCA breakdown →