LINC01143

Across TCGA pan-cancer cohorts, LINC01143 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01143’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where LINC01143 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01143 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

UCEC, LUSC, and LIHC are the cancer types where LINC01143 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01143 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	+0.597	.019	4	view →
LUSC	All	All	+0.553	<.001	4	view →
LIHC	All	All	+0.131	.014	4	view →
KIRC	Male	II,III,IV	−0.052	.002	3	view →
LUAD	Male	All	+0.404	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC01143–UCEC

Open the UCEC breakdown →