LINC01138

Across TCGA patient cohorts, LINC01138 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01138-associated genes across cancer lineages are STAT3_pY705, Tuberin, and Ku80. Each is linked with LINC01138 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01138-to-partner and partner-to-LINC01138 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by LINC01138-low versus LINC01138-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01138→partner) and Y-score (partner→LINC01138) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.467	-2.999	.001	.035	3	1
UCEC	Tuberin →	+0.305	+2.817	.039	.036	3	1
UCEC	Ku80 →	+0.417	+3.183	.001	.010	1	1
UCEC	MEK1 →	+0.531	+3.169	.008	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

STAT3_pY705 by LINC01138 expression — UCEC

Explore this box plot interactively →