LINC01136

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01136 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC01136’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC01136 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01136 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

LIHC, BRCA, and LUAD are the cancer types where LINC01136 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01136 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LIHCMaleAll+0.272<.0018view →
BRCAAllAll+0.320<.0016view →
LUADAllAll+0.246<.0016view →
HNSCAllAll+0.078.0046view →
LUSCAllAll+0.344<.0015view →
THCAAllAll−0.176<.0015view →
KIRCAllAll−0.087.0095view →
KICHAllAll−0.254.0034view →
STADAllAll+0.180.0014view →
CHOLAllAll+0.213.0023view →
UCECAllAll+0.172.0192view →
COADAllAll+0.068.0202view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LINC01136–LIHC

Tumor-vs-normal expression box plot for LINC01136 RNA in LIHC.

Open the LIHC breakdown →

Exploration