LINC01135

Across TCGA pan-cancer cohorts, LINC01135 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of LINC01135’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC01135 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01135 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and COAD are the cancer types where LINC01135 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01135 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−1.952	<.001	11	view →
KICH	Male	All	−1.565	<.001	10	view →
COAD	Female	All	−0.692	<.001	9	view →
LUSC	Male	II,III,IV	−0.563	<.001	8	view →
KIRP	All	All	−0.557	<.001	8	view →
UCEC	All	II,III,IV	−1.214	<.001	6	view →
KIRC	Male	II,III,IV	−0.580	<.001	6	view →
LUAD	All	III,IV	−0.412	<.001	6	view →
STAD	All	All	−0.269	.011	4	view →
BRCA	All	All	−0.162	.011	4	view →
READ	All	III,IV	−0.615	.017	3	view →
LIHC	All	All	+0.270	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

LINC01135–THCA

Open the THCA breakdown →