LINC01126

Across TCGA pan-cancer cohorts, LINC01126 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of LINC01126’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01126 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01126 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

KIRC, THCA, and LIHC are the cancer types where LINC01126 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01126 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.605	<.001	11	view →
THCA	Female	II,III,IV	−0.784	<.001	9	view →
LIHC	Male	All	+0.335	<.001	8	view →
COAD	Male	IV	+0.580	<.001	7	view →
KICH	Female	All	−0.561	<.001	7	view →
BRCA	Female	All	−0.281	<.001	6	view →
KIRP	All	IV	+0.422	.006	5	view →
HNSC	All	II,III,IV	+0.097	.018	5	view →
CHOL	All	All	+0.590	.009	4	view →
LUSC	Male	All	+0.346	<.001	4	view →
STAD	All	All	+0.246	.012	4	view →
LUAD	All	All	+0.268	.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

LINC01126–KIRC

Open the KIRC breakdown →