Across TCGA pan-cancer cohorts, LINC01123 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC01123’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01123 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01123 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.
KIRC, HNSC, and STAD are the cancer types where LINC01123 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01123 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.