LINC01122

Across TCGA pan-cancer cohorts, LINC01122 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC01122’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LINC01122 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01122 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, THCA, and BRCA are the cancer types where LINC01122 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01122 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−0.184	<.001	10	view →
THCA	Female	All	+0.259	<.001	7	view →
BRCA	Female	All	−0.226	<.001	6	view →
KIRC	All	All	−0.047	.001	6	view →
COAD	All	All	−0.015	.005	5	view →
CHOL	All	All	+0.197	.017	2	view →
KIRP	Male	All	−0.073	.006	2	view →
LUSC	All	III,IV	−0.071	.013	2	view →
HNSC	Male	III,IV	+0.058	.041	2	view →
READ	All	All	−0.057	.002	2	view →
LUSC	All	All	+0.121	.032	1	view →
LUAD	Female	III,IV	−0.097	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LINC01122–KICH

Open the KICH breakdown →