LINC01121

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC01121 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01121-associated genes across cancer lineages are EGFR_pY1068, p38-MAPK_pT180_Y182, and p70-S6K_pT389. Each is linked with LINC01121 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01121-to-partner and partner-to-LINC01121 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01121→partner) and Y-score (partner→LINC01121) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEGFR_pY1068 →-0.361-3.000.012.03731
UCECp38-MAPK_pT180_Y182 →-0.592-2.986.022.03731
UCECp70-S6K_pT389 →-0.241-3.000.028.03731
UCECRab25 →-0.450-3.000.018.03731
UCECVHL →-0.998-3.000.010.03731
UCECCaspase-8 →-0.310-3.000.032.03621
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration