LINC01114

Across TCGA pan-cancer cohorts, LINC01114 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LINC01114’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LINC01114 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01114 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

KICH, KIRP, and LUAD are the cancer types where LINC01114 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01114 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−0.466	<.001	9	view →
KIRP	All	All	−0.184	.003	4	view →
LUAD	All	III,IV	−0.046	<.001	4	view →
COAD	All	All	−0.011	.005	4	view →
KIRC	All	All	+0.311	<.001	3	view →
LUSC	Female	All	−0.055	.012	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

LINC01114–KICH

Open the KICH breakdown →