Across TCGA pan-cancer cohorts, LINC01108 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC01108’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LINC01108 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01108 is over-expressed in tumor, although a few such as KIRP and LUAD show the opposite, repressed pattern.
KIRP, LIHC, and LUAD are the cancer types where LINC01108 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01108 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.