LINC01091

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01091 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated LINC01091 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher LINC01091 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC01091 expression acts as an unfavorable survival marker, although some lineages such as PAAD and MESO show a favorable association.

LGG, PAAD, and KIRP are the cancer types where LINC01091 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LGGDFSMedianAll0.6600.806<.00151view →
PAADDFSTertileAll0.4250.172.00142view →
KIRPOSMedianAll0.8940.968.00739view →
MESOOSTertileIII,IV0.7410.425<.00136view →
LUSCDFSMedianAll0.2770.457.00233view →
OVOSQuartileIV0.5240.207.00430view →
HNSCDFSTertileIV0.6950.479.00425view →
UVMOSQuartileAll0.7390.363.00517view →
ACCOSMedianII,III,IV0.3010.734.00415view →
CESCDFSMedianAll0.6640.802.00414view →
SKCMDFSMedianII,III,IV0.3870.169.00910view →
COADDFSMedianIII,IV0.4710.653.01910view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

LINC01091–LGG (DFS)

Kaplan–Meier survival curve for LINC01091 RNA-high vs -low samples in LGG.

Open the LGG breakdown →

Exploration