Across TCGA pan-cancer cohorts, LINC01089 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC01089’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC01089 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01089 is over-expressed in tumor, although a few such as BRCA and KIRC show the opposite, repressed pattern.
LIHC, COAD, and BRCA are the cancer types where LINC01089 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01089 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.