LINC01081

Across TCGA pan-cancer cohorts, LINC01081 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC01081’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where LINC01081 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01081 is over-expressed in tumor, although a few such as BLCA and COAD show the opposite, repressed pattern.

BLCA, COAD, and LUAD are the cancer types where LINC01081 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01081 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	IV	−2.755	<.001	11	view →
COAD	Female	III,IV	−0.744	<.001	11	view →
LUAD	Female	III,IV	−0.985	<.001	9	view →
KIRP	Male	All	−0.251	<.001	8	view →
LUSC	All	III,IV	−1.161	<.001	7	view →
KICH	All	All	−0.356	<.001	7	view →
KIRC	Male	All	−0.152	<.001	7	view →
THCA	All	All	−0.119	<.001	7	view →
STAD	All	All	−0.774	<.001	5	view →
BRCA	All	III,IV	−0.066	.008	4	view →
READ	All	All	−0.815	.007	2	view →
PRAD	All	All	−0.377	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC01081–BLCA

Open the BLCA breakdown →