long intergenic non-protein coding RNA 1058Genealiases: []
Q-omics provides the consensus-scored LINC01058 profile across patient tissues and cancer cell-line models. LINC01058 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, LINC01058 is differentially expressed in 8, with the highest sampling consensus in KICH. Additionally, LINC01058 RNA expression shows 17,115 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight KIRC, KICH, and KIRP as cancer lineages where LINC01058 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01058 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01058 survival associations across molecular data types. LINC01058 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01058 RNA expression–survival associations across cancer types. High LINC01058 expression shows unfavorable associations in LGG, BLCA and THCA, but favorable associations in KIRC, BRCA and UCEC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for LINC01058 RNA expression.
This table summarizes LINC01058 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01058. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01058 shows lower tumor expression in KICH, THCA, BRCA and UCEC and higher tumor expression in KIRP and ESCA. The KICH box plot shows higher LINC01058 RNA expression in normal versus tumor tissue (log2 FC = −1.115, t-test p < 0.001).
This table shows molecular features associated with LINC01058 in patient tissues and cancer cell lines. In patient samples, LINC01058 shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set.
