LINC01053

Across TCGA patient cohorts, LINC01053 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,672 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC01053-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Nucleus organization, and Positive regulation of DNA biosynthetic process. Each is linked with LINC01053 in more than 13 cancer types. Because this analysis shows association rather than direction, both LINC01053-to-partner and partner-to-LINC01053 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by LINC01053-low versus LINC01053-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01053→partner) and Y-score (partner→LINC01053) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.078	+0.218	<.001	<.001	3	14
STAD	Nucleus organization →	+0.079	+0.208	<.001	<.001	3	14
STAD	Positive regulation of DNA biosynthetic process →	+0.080	+0.196	<.001	<.001	3	13
STAD	Positive regulation of protein modification by small protein conjugation or removal →	+0.078	+0.206	<.001	<.001	3	13
ESCA	Regulation of double-strand break repair →	+0.075	+0.073	<.001	.002	3	13
ESCA	Regulation of DNA repair →	+0.077	+0.102	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,672 associations by consensus.

Positive regulation of DNA metabolic process by LINC01053 expression — STAD

Explore this box plot interactively →