LINC01050

Across TCGA pan-cancer cohorts, LINC01050 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LINC01050 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LINC01050 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01050 expression acts as an unfavorable survival marker, although some lineages such as CHOL and DLBC show a favorable association.

UVM, KIRC, and THYM are the cancer types where LINC01050 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.619	0.901	<.001	96	view →
KIRC	DFS	Tertile	All	0.727	0.833	<.001	78	view →
THYM	DFS	Tertile	All	0.804	0.924	.009	66	view →
ACC	DFS	Quartile	III,IV	0.045	0.407	<.001	58	view →
LUAD	DFS	Tertile	III,IV	0.473	0.809	.003	46	view →
STAD	DFS	Tertile	All	0.384	0.653	.001	36	view →
MESO	OS	Median	III,IV	0.446	0.694	.004	32	view →
LGG	OS	Tertile	All	0.312	0.460	.001	21	view →
LAML	DFS	Tertile	All	0.208	0.519	.006	18	view →
BLCA	DFS	Median	All	0.264	0.422	.012	17	view →
READ	DFS	Tertile	All	0.471	0.765	.026	16	view →
CHOL	DFS	Median	II,III,IV	0.623	0.115	.003	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

LINC01050–UVM (OS)

Open the UVM breakdown →