Across TCGA pan-cancer cohorts, LINC01046 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC01046’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC01046 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01046 is over-expressed in tumor.
LIHC are the cancer types where LINC01046 tumor–normal differential expression is most reproducible.