LINC01028

Across TCGA pan-cancer cohorts, LINC01028 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC01028’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01028 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01028 is over-expressed in tumor, although a few such as HNSC and BRCA show the opposite, repressed pattern.

HNSC, BRCA, and COAD are the cancer types where LINC01028 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01028 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	−0.246	.010	7	view →
BRCA	All	III,IV	−1.252	<.001	6	view →
COAD	Male	IV	−0.056	.005	6	view →
KIRC	All	All	−0.056	<.001	6	view →
LUAD	All	All	−0.359	<.001	5	view →
UCEC	All	II,III,IV	−0.452	.015	4	view →
LUSC	All	All	−0.282	<.001	4	view →
THCA	Male	II,III,IV	−0.187	.004	4	view →
STAD	All	II,III,IV	−0.139	.006	4	view →
KICH	All	All	−0.084	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC01028–HNSC

Open the HNSC breakdown →