LINC01023

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01023 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC01023’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC01023 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01023 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

LUAD, THCA, and COAD are the cancer types where LINC01023 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01023 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUADMaleII,III,IV−0.866<.00110view →
THCAMaleAll−0.798<.0019view →
COADMaleII,III,IV−0.583<.0017view →
BRCAFemaleII,III,IV−0.724<.0016view →
KICHAllAll−0.970<.0014view →
CHOLAllAll+0.956<.0013view →
LIHCAllAll+0.443.0033view →
STADAllAll−0.423.0123view →
LUSCMaleIII,IV−1.364.0052view →
UCECAllII,III,IV−0.848.0442view →
KIRPAllAll−0.727<.0012view →
KIRCAllAll−0.364.0072view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LINC01023–LUAD

Tumor-vs-normal expression box plot for LINC01023 RNA in LUAD.

Open the LUAD breakdown →

Exploration