LINC01011

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01011 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC01011’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01011 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01011 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KIRC, KICH, and LIHC are the cancer types where LINC01011 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01011 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCFemaleIII,IV+0.699<.00112view →
KICHFemaleII,III,IV−1.578<.00111view →
LIHCFemaleII,III,IV+0.742<.0019view →
COADMaleII,III,IV+0.701<.0017view →
CHOLMaleAll+2.021<.0015view →
KIRPAllIV+0.495.0164view →
UCECAllAll−0.344.0264view →
LUADAllAll+0.244.0034view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LINC01011–KIRC

Tumor-vs-normal expression box plot for LINC01011 RNA in KIRC.

Open the KIRC breakdown →

Exploration