LINC01001

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC01001 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01001-associated genes across cancer lineages are MIR4654, CA15P2, and RNA5SP321. Each is linked with LINC01001 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01001-to-partner and partner-to-LINC01001 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4654 grouped by LINC01001-low versus LINC01001-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01001→partner) and Y-score (partner→LINC01001) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR4654 →+0.902+5.771<.001.00331
UCECCA15P2 →+0.122+5.031.003.00931
UCECRNA5SP321 →+2.154+5.358<.001.00631
UCECRNA5SP205 →+1.566+5.852<.001.00331
UCECSNORA10B →+0.602+5.031<.001.00931
UCECRAC1P7 →+0.265+5.771.006.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MIR4654 by LINC01001 expression — UCEC

Box plot of MIR4654 in LINC01001-low vs LINC01001-high samples in UCEC.

Explore this box plot interactively →

Exploration