long intergenic non-protein coding RNA 994Genealiases: []
Q-omics provides the consensus-scored LINC00994 profile across patient tissues and cancer cell-line models. LINC00994 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, LINC00994 is differentially expressed in 7, with the highest sampling consensus in THCA. Additionally, LINC00994 RNA expression shows 8,074 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UCS, THCA, and TGCT as cancer lineages where LINC00994 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00994 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00994 survival associations across molecular data types. LINC00994 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00994 RNA expression–survival associations across cancer types. High LINC00994 expression shows unfavorable associations in KIRC and UCEC, but favorable associations in UCS, LGG, KIRP and MESO. The UCS Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .004). Together, the overview and detailed table identify UCS as the clearest survival context for LINC00994 RNA expression.
This table summarizes LINC00994 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00994. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00994 shows lower tumor expression in THCA, KICH, LUSC, BRCA and COAD and higher tumor expression in HNSC. The THCA box plot shows higher LINC00994 RNA expression in normal versus tumor tissue (log2 FC = −0.055, t-test p = .009).
This table shows molecular features associated with LINC00994 in patient tissues and cancer cell lines. In patient samples, LINC00994 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
