LINC00993

Across TCGA pan-cancer cohorts, LINC00993 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC00993’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00993 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00993 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

HNSC, KICH, and KIRC are the cancer types where LINC00993 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00993 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.112	.006	8	view →
KICH	All	All	+0.280	<.001	5	view →
KIRC	All	All	−0.016	.011	3	view →
BLCA	All	All	+0.229	.042	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

LINC00993–HNSC

Open the HNSC breakdown →