Across TCGA pan-cancer cohorts, LINC00972 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC00972’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00972 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00972 is over-expressed in tumor.
HNSC and LUSC are the cancer types where LINC00972 tumor–normal differential expression is most reproducible.