LINC00941

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00941 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of LINC00941’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00941 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00941 is over-expressed in tumor, although a few such as PRAD show the opposite, repressed pattern.

HNSC, COAD, and STAD are the cancer types where LINC00941 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00941 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCFemaleIV+2.810<.00112view →
COADMaleII,III,IV+1.066<.0018view →
STADAllAll+0.957<.0018view →
THCAAllAll+0.308<.0017view →
LUSCMaleII,III,IV+1.389<.0016view →
KIRCMaleAll+0.319.0016view →
LUADAllAll+0.737<.0015view →
LIHCAllAll+0.237.0054view →
CHOLAllAll+2.250<.0013view →
ESCAAllAll+2.000.0092view →
PAADAllAll+1.757.0042view →
READMaleAll+1.530.0372view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

LINC00941–HNSC

Tumor-vs-normal expression box plot for LINC00941 RNA in HNSC.

Open the HNSC breakdown →

Exploration