LINC00939

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00939 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC00939’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00939 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00939 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KIRC, KICH, and STAD are the cancer types where LINC00939 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00939 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleII,III,IV+0.228<.00110view →
KICHAllII,III,IV−0.127<.0019view →
STADAllAll+0.193.0034view →
COADAllAll+0.179.0143view →
PRADAllAll+0.571<.0012view →
PAADAllAll+0.337.0132view →
READMaleAll+0.216.0282view →
KIRPAllAll+0.206.0082view →
LIHCFemaleIII,IV+0.386.0371view →
THCAAllAll−0.021.0281view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC00939–KIRC

Tumor-vs-normal expression box plot for LINC00939 RNA in KIRC.

Open the KIRC breakdown →

Exploration