Across TCGA pan-cancer cohorts, LINC00929 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC00929’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC00929 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00929 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.
LUSC, BRCA, and LUAD are the cancer types where LINC00929 tumor–normal differential expression is most reproducible.