LINC00927

Across TCGA pan-cancer cohorts, LINC00927 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC00927’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC00927 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00927 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BRCA, CHOL, and HNSC are the cancer types where LINC00927 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00927 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.020	.005	4	view →
CHOL	Female	All	+0.060	.017	2	view →
HNSC	Female	IV	+0.010	.049	1	view →
THCA	Male	II,III,IV	−0.008	.022	1	view →
LUSC	All	All	+0.004	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC00927–BRCA

Open the BRCA breakdown →