LINC00900

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00900 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of LINC00900’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00900 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00900 is over-expressed in tumor, although a few such as HNSC and UCEC show the opposite, repressed pattern.

KIRC, HNSC, and KIRP are the cancer types where LINC00900 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00900 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleAll+0.913<.00112view →
HNSCMaleIV−0.914<.00110view →
KIRPMaleAll+0.807<.0018view →
THCAFemaleIII,IV+1.128<.0017view →
UCECAllII,III,IV−1.053<.0016view →
LUADAllAll+0.444<.0015view →
COADAllAll−0.166.0034view →
KICHMaleII,III,IV−0.195.0093view →
LIHCAllAll+0.095.0203view →
PRADAllAll−0.538<.0012view →
LUADAllIV−0.400.0062view →
CHOLAllAll+0.342.0022view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

LINC00900–KIRC

Tumor-vs-normal expression box plot for LINC00900 RNA in KIRC.

Open the KIRC breakdown →

Exploration