LINC00899

Across TCGA pan-cancer cohorts, LINC00899 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC00899’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00899 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00899 is over-expressed in tumor, although a few such as KIRC and UCEC show the opposite, repressed pattern.

HNSC, KIRC, and UCEC are the cancer types where LINC00899 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00899 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.452	<.001	8	view →
KIRC	All	II,III,IV	−0.354	.001	8	view →
UCEC	All	All	−1.343	<.001	6	view →
BRCA	Female	All	−0.566	<.001	6	view →
LUAD	All	III,IV	−0.516	<.001	6	view →
LIHC	Male	All	+0.395	<.001	6	view →
CHOL	Male	All	+1.275	<.001	5	view →
COAD	All	All	+0.300	.004	4	view →
LUSC	All	III,IV	−0.794	.005	2	view →
KICH	All	All	−0.571	.006	2	view →
BLCA	Male	IV	−1.219	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LINC00899–HNSC

Open the HNSC breakdown →