LINC00894

Across TCGA pan-cancer cohorts, LINC00894 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC00894’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00894 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00894 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

HNSC, COAD, and LIHC are the cancer types where LINC00894 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00894 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.220	<.001	11	view →
COAD	All	IV	+0.868	<.001	10	view →
LIHC	All	II,III,IV	+0.290	<.001	8	view →
KIRC	All	All	+0.230	<.001	7	view →
STAD	All	II,III,IV	+0.439	.004	4	view →
CHOL	All	All	+0.816	.012	2	view →
READ	All	All	+0.736	.007	2	view →
UCEC	All	All	−0.315	.032	2	view →
BRCA	Female	All	−0.231	.024	2	view →
KIRP	All	All	+0.286	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC00894–HNSC

Open the HNSC breakdown →