long intergenic non-protein coding RNA 891Genealiases: []
Q-omics provides the consensus-scored LINC00891 profile across patient tissues and cancer cell-line models. LINC00891 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, LINC00891 is differentially expressed in 14, with the highest sampling consensus in LUAD. Additionally, LINC00891 RNA expression shows 19,424 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight HNSC, LUAD, and LSCC as cancer lineages where LINC00891 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00891 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00891 survival associations across molecular data types. LINC00891 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00891 RNA expression–survival associations across cancer types. High LINC00891 expression shows unfavorable associations in KIRC and ACC, but favorable associations in HNSC, UCEC, SKCM and SARC. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .003). Together, the overview and detailed table identify HNSC as the clearest survival context for LINC00891 RNA expression.
This table summarizes LINC00891 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00891. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00891 shows lower tumor expression in LUAD, COAD, LUSC, BLCA and UCEC and higher tumor expression in THCA. The LUAD box plot shows higher LINC00891 RNA expression in normal versus tumor tissue (log2 FC = −0.976, t-test p < 0.001).
This table shows molecular features associated with LINC00891 in patient tissues and cancer cell lines. In patient samples, LINC00891 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
