LINC00888

Across TCGA pan-cancer cohorts, LINC00888 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC00888’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC00888 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00888 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

LUAD, THCA, and BRCA are the cancer types where LINC00888 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00888 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	+0.789	<.001	7	view →
THCA	Male	III,IV	−0.762	<.001	7	view →
BRCA	All	III,IV	−0.817	<.001	6	view →
COAD	Female	II,III,IV	+0.719	<.001	6	view →
BLCA	All	All	+0.646	.024	4	view →
ESCA	All	All	+1.083	.020	2	view →
UCEC	All	II,III,IV	+0.714	.029	2	view →
KICH	All	All	−0.450	.014	2	view →
LUSC	All	All	+0.419	.011	2	view →
READ	All	II,III,IV	+0.857	.024	1	view →
CHOL	Female	All	+0.850	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LINC00888–LUAD

Open the LUAD breakdown →