LINC00885

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00885 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC00885’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00885 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00885 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and THCA are the cancer types where LINC00885 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00885 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleAll−1.467<.00112view →
KIRPMaleII,III,IV−1.758<.00111view →
THCAMaleAll−0.324<.0019view →
LIHCMaleII,III,IV−1.523<.0018view →
BLCAAllAll+1.346.0057view →
LUSCFemaleAll+1.964<.0016view →
UCECAllAll+1.139<.0016view →
LUADMaleII,III,IV−0.725<.0016view →
COADAllII,III,IV+0.079.0194view →
PRADAllAll−0.725<.0012view →
STADAllIV+0.136.0042view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

Exploration